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Room: 325, Bldg: IBES

February 2018

EMBS: Regulation of cardiomyocyte electrical activity by cardiac fibroblasts in innovative 3D in vitro cellular cross-talk platforms

February 28, 2018 @ 6:30 pm - 7:30 pm

Cardiac fibroblasts (CFs) are known to regulate cardiomyocyte (CM) function in vivo and in two-dimensional in vitro cultures. Multicellular spheroids generated through cellular self-assembly provide cytoarchitectural complexities of native tissue including three-dimensionality, extensive cell-cell contacts, and appropriate cell-ECM interactions. They are increasingly suggested as building blocks for larger engineered tissues to achieve shapes, organization, heterogeneity, and other biomimetic complexities. Application of these tissue culture platforms is of particular importance in cardiac research as the myocardium is comprised of distinct but…

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